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The Br, Fe, Rb, Sr, and Zn contents and interrelation in intact and morphologic normal prostate tissue of adult men investigated by energy‐dispersive X‐ray fluorescent analysis
Author(s) -
Zaichick Sofia,
Zaichick Vladimir
Publication year - 2011
Publication title -
x‐ray spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.447
H-Index - 45
eISSN - 1097-4539
pISSN - 0049-8246
DOI - 10.1002/xrs.1370
Subject(s) - prostate , zinc , bromine , chemistry , mass fraction , prostate gland , fluorescence , radiochemistry , analytical chemistry (journal) , medicine , chromatography , cancer , physics , organic chemistry , quantum mechanics
A method for radionuclide‐induced ( 109 Cd) energy‐dispersive X‐ray fluorescent (EDXRF) was used to determine Br, Fe, Rb, Sr, and Zn contents in intact and morphologic normal prostate tissues. Prostates were removed at necropsy from 64 men (mean age 36.5 years, range 13–60) who had died suddenly. All materials were divided into two parts. One part was morphologically examined, whereas chemical element contents of the other were estimated. Mean values (M ± SΕΜ) for mass fraction of Br, Fe, Rb, Sr, and Zn (mg kg −1 on dry‐weight basis) in the intact and morphologic normal prostate tissue were 35.5 ± 4.0, 107 ± 5.4, 17.1 ± 0.8, 1.9 ± 0.3, and 850 ± 79, respectively. Mean values (M ± SΕΜ) for Zn/Fe, Zn/Rb, and Zn/Sr ratios of mass fraction were 8.72 ± 0.80, 57.4 ± 7.2, and 567 ± 82, respectively. A strongly pronounced tendency of age‐related exponential increase in Zn mass fraction as well an increase in Zn/Fe, Zn/Rb, and Zn/Sr ratios in prostate was observed. A significant positive correlation was seen between the prostatic zinc and iron contents ( p ≤ 0.05, r = 0.22) and between the prostatic zinc and bromine contents ( p ≤ 0.01, r = 0.43). Copyright © 2011 John Wiley & Sons, Ltd.