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Advances of functional nanomaterials for cancer immunotherapeutic applications
Author(s) -
Hao Yuhao,
Zhou Xingyu,
Li Rui,
Song Zechenxi,
Min Yuanzeng
Publication year - 2019
Publication title -
wiley interdisciplinary reviews: nanomedicine and nanobiotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 72
eISSN - 1939-0041
pISSN - 1939-5116
DOI - 10.1002/wnan.1574
Subject(s) - nanomedicine , immunotherapy , nanocarriers , cancer immunotherapy , cancer , immune system , medicine , cancer therapy , drug , nanotechnology , immunology , pharmacology , materials science , nanoparticle
Immunotherapy has made great progress by modulating the body's own immune system to fight against cancer cells. However, the low response rates of related drugs limit the development of immunotherapy strategies. Fortunately, the advantages of nanotechnology can just make up for this shortcoming. Nanocarriers of diverse systems are utilized to co‐deliver antigens and adjuvants, combined with drugs for immunomodulatory, such as chemotherapy, radiotherapy, and photodynamic. Here we review recent studies on immunotherapy with biomimetic, organic, and inorganic nanomaterials. They are going to potentially overcome the drawbacks in cancer immunotherapy with delivering immunomodulatory drugs, delivering cancer vaccine, and monitoring the immune systems. This article is characterized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease