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Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes
Author(s) -
Cui Liyang,
Rao Jianghong
Publication year - 2016
Publication title -
wiley interdisciplinary reviews: nanomedicine and nanobiotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 72
eISSN - 1939-0041
pISSN - 1939-5116
DOI - 10.1002/wnan.1418
Subject(s) - photoacoustic imaging in biomedicine , molecular imaging , nanotechnology , nanoparticle , materials science , nanomaterials , optical imaging , biocompatible material , polymer , drug delivery , preclinical imaging , in vivo , biomedical engineering , optics , medicine , physics , microbiology and biotechnology , composite material , biology
As an emerging class of optical nanomaterials, semiconducting polymer nanoparticles ( SPNs ) are highly photostable, optically active and versatile in chemistry; these properties make them attractive as molecular imaging agents to enable imaging of biological events and functionalities at multiple scales. More recently, a variety of SPNs have been found to exhibit high photoacoustic properties, and further empowered photoacoustic imaging for contrast enhanced in vivo molecular imaging. Target‐sensitive components can be incorporated in the SPNs to create activatable imaging probes to sense and monitor the target dynamics in living objects. Intrinsically biophotonic and biocompatible, SPNs can be further engineered for multimodal imaging and for real‐time imaging of drug delivery. WIREs Nanomed Nanobiotechnol 2017, 9:e1418. doi: 10.1002/wnan.1418 This article is categorized under: Diagnostic Tools > In Vivo Nanodiagnostics and Imaging