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An overview of optical coherence tomography for ovarian tissue imaging and characterization
Author(s) -
Wang Tianheng,
Brewer Molly,
Zhu Quing
Publication year - 2014
Publication title -
wiley interdisciplinary reviews: nanomedicine and nanobiotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 72
eISSN - 1939-0041
pISSN - 1939-5116
DOI - 10.1002/wnan.1306
Subject(s) - optical coherence tomography , ovarian tissue , ovarian cancer , medicine , ovarian tissue cryopreservation , modalities , radiology , stage (stratigraphy) , ovary , pathology , cancer , biology , paleontology , fertility , population , social science , environmental health , sociology , fertility preservation
Ovarian cancer has the lowest survival rate among all the gynecologic cancers because it is predominantly diagnosed at late stages due to the lack of reliable symptoms and efficacious screening techniques. Optical coherence tomography ( OCT ) is an emerging technique that provides high‐resolution images of biological tissue in real time, and demonstrates great potential for imaging of ovarian tissue. In this article, we review OCT studies for visualization and diagnosis of human ovaries as well as quantitative extraction of ovarian tissue optical properties for classifying normal and malignant ovaries. OCT combined with other imaging modalities to further improve ovarian tissue diagnosis is also reviewed. WIREs Nanomed Nanobiotechnol 2015, 7:1–16. doi: 10.1002/wnan.1306 This article is categorized under: Diagnostic Tools > Biosensing Therapeutic Approaches and Drug Discovery > Emerging Technologies Diagnostic Tools > In Vivo Nanodiagnostics and Imaging