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At the nanoscale: nanohemostat, a new class of hemostatic agent
Author(s) -
EllisBehnke Rutledge
Publication year - 2010
Publication title -
wiley interdisciplinary reviews: nanomedicine and nanobiotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.175
H-Index - 72
eISSN - 1939-0041
pISSN - 1939-5116
DOI - 10.1002/wnan.110
Subject(s) - hemostat , nanotechnology , ligature , nanoscopic scale , biomedical engineering , medicine , surgery , materials science
Three basic categories of hemostats are widely used in surgery today: chemical agents, thermal devices, and mechanical methods that use pressure or ligature to slow bleeding. Each has its benefits and limitations. However, nanotechnology is rapidly ushering in new medical technologies. This review focuses on the ‘nanohemostat’, a new class of hemostatic agent that stops bleeding in less than 15 seconds by using (RADA)4, referred to as nanohemostat‐1 (NHS‐1), a synthetic biological material that self‐assembles at the nanoscale when applied to a wound, and compares it to the characteristics of the ‘ideal hemostat’. WIREs Nanomed Nanobiotechnol 2011 3 70–78 DOI: 10.1002/wnan.110 This article is categorized under: Implantable Materials and Surgical Technologies > Nanomaterials and Implants Implantable Materials and Surgical Technologies > Nanotechnology in Tissue Repair and Replacement Implantable Materials and Surgical Technologies > Nanoscale Tools and Techniques in Surgery