Open AccessSuccessful management of feline pemphigus foliaceus with pentoxifylline and topical hydrocortisone aceponate
Author(s) -
Hobi Stefan,
Beatty Julia A.,
Sandy Jeanine R.,
Barrs Vanessa R.
Publication year - 2022
Publication title -
veterinary medicine and science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.485
H-Index - 11
ISSN - 2053-1095
DOI - 10.1002/vms3.768
Subject(s) - pemphigus foliaceus , medicine , pemphigus , histopathology , miltefosine , dermatology , pathology , immunology , antibody , autoantibody , leishmaniasis , visceral leishmaniasis
The treatment regimen for feline pemphigus foliaceus (PF), an autoimmune disease caused by auto‐antibodies against proteins of the desmosome junction, usually includes high doses of oral or parenteral immunosuppressive drugs, typically glucocorticoids. This case adds to a growing body of evidence that topical hydrocortisone aceponate is effective for the treatment of feline PF, and demonstrates the practical use of a non‐invasive diagnostic method for histopathology when owners refuse a biopsy to support a clinical diagnosis of PF. Finally, this case highlights an international trend of owner‐initiated treatment of feline infectious peritonitis (FIP) using unlicensed, unregistered drugs.