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A new phenolic compound from the lichen Parmotrema praesorediosum (Nyl.) Hale
Author(s) -
Chi Huynh Bui Linh,
Van Muoi Bui,
Thu Nguyen Thi Hoai,
Phung Nguyen Kim Phi
Publication year - 2021
Publication title -
vietnam journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2572-8288
pISSN - 0866-7144
DOI - 10.1002/vjch.202060096
Subject(s) - lichen , chemistry , parmeliaceae , traditional medicine , botany , medicine , biology , biochemistry , ascomycota , gene
Chemical investigation of the lichen Parmotrema praesorediosum (Nyl.) Hale led to isolate six phenolic compounds including praesorediosic ( 1 ), orcinol ( 2 ), orselinic acid ( 3 ), lecanorin ( 4 ), isolecanoric acid ( 5 ) and virensic acid ( 6 ). Among them, compound 1 appeared to be found for the first time in the nature. The structure of these compounds was elucidated by spectroscopic analyses of HRESIMS and NMR as well as the comparison of their NMR data with those in the literature. These compounds were evaluated for their cytotoxicity using sulforhodamine‐B assay against HeLa (human epithelial carcinoma), NCI‐H460 (human lung cancer), HepG2 (liver hepatocellular carcinoma) and MCF‐7 (human breast cancer) cell lines.