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New iridoid from Valeriana hardwickii Wall.
Author(s) -
Hong Le Thi Thu,
Huyen Tran Thi,
Tri Le Minh,
Hien Tran Duy,
Loi Huynh
Publication year - 2021
Publication title -
vietnam journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2572-8288
pISSN - 0866-7144
DOI - 10.1002/vjch.202000073
Subject(s) - traditional medicine , medicine
A new iridoid, (4 S ,5 R ,6 S ,7 S ,9 S )‐7,10,11‐trihydroxy dihydronepetalactone ( 1 ) together with four known flavonoids including linarin, neodiosmin, neobudofficide and rhoifolin were isolated from aerial parts of Valeriana hardwickii Wall.. Chemical structures were elucidated by extensive spectroscopic analyses including ESI‐HRMS and 1D, 2D‐NMR spectral data as well as by comparison with those reported in the literatures. Compound 1 showed no cytotoxic activity toward three human cancer cell lines (CCRF‐CEM, MDA‐MB‐231 and HCT‐116).