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Isoflavones from Placolobium vietnamense, an indigenous plant of Vietnam
Author(s) -
Lien Do Thi My,
Tuyet Huynh Thi Ngoc,
Quyen Tran Hong Ngoc,
Truong Tuong Lam,
Hang Nguyen Thi Thu,
Thao Nguyen Thi Ngoc,
Dung Nguyen Thi My
Publication year - 2021
Publication title -
vietnam journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2572-8288
pISSN - 0866-7144
DOI - 10.1002/vjch.202000037
Subject(s) - isoflavones , indigenous , traditional medicine , geography , biology , medicine , biochemistry , ecology
Placolobium vietnamense N.D.Khoi & Yakovlev (Fabaceae) is an indigenous plant of Vietnam. Up to now, this plant has not yet been chemically and biologically studied. In this paper, six isoflavones including afrormosin ( 1 ), cladrastin ( 2) , 8‐ O ‐methylretusin (3) , millesianin C (4 ), barbigerone ( 5 ), and durallone (6) were isolated from the ethyl acetate extract of the stem bark of Placolobium vietnamense . Their structures were established by means of physical data (ESI MS, 1D and 2D NMR) and evaluated for the cytotoxic activities against liver hepatocellular carcinoma (HepG2), human lung cancer (NCI‐H460), human epithelial carcinoma (HeLa) and human breast cancer (MCF‐7) cell lines. This is the first report on phytochemical studies of this plant.