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Mini Review: Anticancer activity of diterpenoid peroxides
Author(s) -
Sikorsky Tatyana V.,
Ermolenko Ekaterina V.,
Gloriozova Tatyana A.,
Dembitsky Valery M.
Publication year - 2020
Publication title -
vietnam journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2572-8288
pISSN - 0866-7144
DOI - 10.1002/vjch.202000014
Subject(s) - antiprotozoal , terpenoid , antifungal , bark (sound) , traditional medicine , chemistry , stereochemistry , biology , medicine , biochemistry , microbiology and biotechnology , in vitro , ecology
In this review, we present about 100 diterpenoid hydro‐ and endoperoxides isolated from algae, liverworts, leaves, bark, roots and other parts of plants. for the vast majority of hydroperoxides, antitumor activity dominates with a confidence of 63 % to 94 %. And for individual hydroperoxides, antiprotozoal ( Plasmodium ) activity was also found. For endoperoxides, antitumor activity is dominant with a confidence of 59 to 90 percent. Anti‐inflammatory, antibacterial and antifungal activities have also been detected for individual endoperoxides. The data obtained are of interest to pharmacologists, medical professionals, as well as to the pharmaceutical industry.