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Chemical constituents from the soft coral Sinularia digitata
Author(s) -
Huong Nguyen Thi,
Ngoc Ninh Thi,
Hanh Tran Thi Hong,
Quang Tran Hong,
Cuong Nguyen Xuan,
Nam Nguyen Hoai,
Van Minh Chau
Publication year - 2019
Publication title -
vietnam journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2572-8288
pISSN - 0866-7144
DOI - 10.1002/vjch.201900112
Subject(s) - coral , chemistry , methanol , stereochemistry , chemical constituents , chromatography , organic chemistry , biology , ecology
Using various chromatographic separations, six known compounds namely (1 R *,2 E ,4 R *,7 E ,10 S *,11 S *,12 R *)‐10,18‐diacetoxy‐dolabella‐2,7‐dien‐6‐one ( 1 ), emblide ( 2 ), sarcophine ( 3 ), (3 R )‐4‐[(2 R ,4 S )‐4‐acetoxy‐2‐hydoxy‐2,6,6‐trimethylcyclohexylidene‐3‐en‐2‐one ( 4 ), 3 β ‐hydroxypregna‐5,16‐dien‐20‐one ( 5 ), and 3 β ‐hydroxyandrost‐5‐en‐17‐one ( 6 ) were isolated from a methanol extract of the Vietnamese soft coral Sinularia digitata . The structural elucidation was confirmed by extensive analysis of the 1D and 2D NMR spectroscopic data as well as comparison of them with the reported values.