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13(18)‐Ene ursan glycosides from Allium ascalonicum
Author(s) -
Mai Nguyen Thi,
Lan Hoang Thi Tuyet,
Trang Do Thi,
Dung Duong Thi,
Tai Bui Huu,
Nhiem Nguyen Xuan,
Van Kiem Phan
Publication year - 2020
Publication title -
vietnam journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2572-8288
pISSN - 0866-7144
DOI - 10.1002/vjch.201900106
Subject(s) - chemistry , glycoside , allium , lactone , traditional medicine , stereochemistry , botany , medicine , biology
Allium ascalonicum L. is belong to Alliaceae family, which is common vegetables and used to treat typhoid, colds, headaches, bloating and poisoning, eyes blurred deaf ears, burnt blood, pregnant women, breast swelling, children wicked and swollen in folk medicine. Using combined chromatographic methods, four 13,18‐en ursan compounds were isolated from methanol extract of the roots of Allium ascalonicum . Their chemical structures were elucidate as 3 β ,12 α ,19 α ‐trihydroxyurs‐13(18)‐en‐28,20β‐lactone ( 1 ), 3 β ,12 α ,19 α ‐trihydroxyurs‐13(18)‐ene‐28,20 β ‐lactone‐3‐ O ‐(3‐ O ‐ β ‐D‐glucopyranosyl‐2‐ O ‐ α ‐L‐rhamnopyranosyl)‐ α ‐L‐arabinopyranoside ( 2 ), 3 β ,12 α ,19 α ‐trihydroxyurs‐13(18)‐ene‐28,20 β ‐lactone‐3‐ O ‐[3‐ O ‐( β ‐D‐glucopyranosyl‐2‐ O ‐ β ‐D‐glucopyranosyl)‐2‐ O ‐ α ‐L‐rhamnopyranosyl]‐ α ‐L‐arabinopyranoside ( 3 ), 3 β ,12 β ,19 α ‐trihydroxyurs‐13(18)‐ene‐28,20 β ‐lactone‐3‐ O ‐(3‐ O ‐ β ‐D‐glucopyranosyl‐2‐ O ‐ α ‐L‐rhamnopyranosyl)‐ α ‐L‐arabinopyranoside ( 4 ) on the basis of spectroscopic evidences and in comparison with those reported in the literature. All these compounds were isolated from Allium genus for the first time.