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The chemical constituents and biological activity of some sponges in Northern Vietnam: A review
Author(s) -
Van Kiem Phan,
Van Minh Chau,
Nhiem Nguyen Xuan,
Tai Bui Huu,
Yen Pham Hai,
Hang Dan Thi Thuy,
Dung Duong Thi,
Cuc Nguyen Thi,
Trang Do Thi,
Yen Duong Thi Hai,
Van Doan Vu,
Hoang Nguyen Huy,
Huong Phan Thi Thanh,
Nam Nguyen Hoai,
Cuong Nguyen Xuan
Publication year - 2019
Publication title -
vietnam journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2572-8288
pISSN - 0866-7144
DOI - 10.1002/vjch.201900041
Subject(s) - sponge , circular dichroism , chemical composition , chemical structure , chemical constituents , chemistry , cytotoxicity , chemical shift , stereochemistry , organic chemistry , biology , biochemistry , botany , chromatography , in vitro
Chemical composition and biological activity of sponges have been studied by the authors since 2006. So far, the authors have studied about 30 species of sponges, mainly collected cross in the sea of Northern Vietnam. Over 250 compounds have been isolated and elucidated their chemical structures. Among them, there are more than 50 compounds with new chemical structures. In addition to NMR and HRMS spectra, many compounds with an unequal chemical structure are also determined by Circular Dichroism spectrometry. Some isolated compounds exhibited outstanding potential for cancer cytotoxicity and anti‐inflammatory effects.