Open AccessSelf‐assembled organic/metal ion nanohybrids for theranostics
Author(s) -
Zhang Kai,
Zhao Nana,
Xu FuJian
Publication year - 2020
Publication title -
view
Language(s) - English
Resource type - Journals
eISSN - 2688-268X
pISSN - 2688-3988
DOI - 10.1002/viw2.17
Subject(s) - nanotechnology , materials science , biomolecule , biocompatibility , cancer therapy , metal ions in aqueous solution , surface modification , organic molecules , metal , molecule , chemistry , cancer , organic chemistry , medicine , metallurgy
Owing to their remarkable physicochemical and favorable biological properties, self‐assembled organic/metal ions nanohybrids show great potential for constructing multifunctional nanoplatforms of cancer theranostics. By tailoring the structural components of organic blocks and metal ions, various nanoplatforms with integrated properties can be manufactured. These nanoplatforms offer different capacities, including high loading effect, facile modification/functionalization, and excellent biocompatibility, which are beneficial for applications in bioimaging and cancer treatments. This review focuses on the design, fabrication, properties of organic/metal ions nanohybrids, and their applications in biosensing, bioimaging, therapy, and bioimaging‐guided therapy of cancer. Various research works related to organic/metal ions nanohybrids toward cancer theranostics are highlighted. By presenting and summarizing these research works and discoveries, the species of organic blocks are classified into synthetic organic molecules and biomolecules. Besides, the intrinsic properties and synergistic characteristics of organic blocks and metal ions are also discussed. The prospects and challenges for future researches in this field are also proposed.