Open AccessFrontispiece: Exosome therapeutics for COVID‐19 and respiratory viruses (View 3/2021)
Author(s) -
Popowski Kristen D.,
Dinh PhuongUyen C.,
George Arianna,
Lutz Halle,
Cheng Ke
Publication year - 2021
Publication title -
view
Language(s) - English
Resource type - Reports
eISSN - 2688-268X
pISSN - 2688-3988
DOI - 10.1002/viw2.149
Subject(s) - exosome , microvesicles , virology , covid-19 , endosome , extracellular vesicles , extracellular vesicle , respiratory system , biology , computational biology , medicine , microbiology and biotechnology , genetics , pathology , gene , microrna , infectious disease (medical specialty) , disease , anatomy , intracellular
In article number 20200186, Ke Cheng, Phuong‐Uyen C. Dinh, Kristen Popowski and their co‐workers describe the relationship between nanoparticles and respiratory viruses, to emphasize the clinical translation of exosome therapeutics for diseases such as SARS‐CoV‐2 infection. A naturally occurring extracellular vesicle, exosomes utilize similar endosomal sorting pathways and uptake mechanisms as viruses. In this cover, the gears represent the parallels between nanoparticle and viral mechanisms within the lung and how these biological systems can be utilized to enhance drug delivery and efficacy.