Open AccessTailoring nanoparticles for targeted drug delivery: From organ to subcellular level
Author(s) -
Liang Tingxizi,
Xing Zejing,
Jiang Liping,
Zhu JunJie
Publication year - 2021
Publication title -
view
Language(s) - English
Resource type - Journals
eISSN - 2688-268X
pISSN - 2688-3988
DOI - 10.1002/viw.20200131
Subject(s) - nanomedicine , drug delivery , drug , targeted drug delivery , nanotechnology , nucleic acid , chemistry , pharmacology , computational biology , nanoparticle , medicine , biology , materials science , biochemistry
An effective dose at specific sites is of paramount importance for disease therapy. While therapeutic reagents such as small molecule drugs, nucleic acids, peptides, and proteins are suffered from degradation or clearance by physiological environment, nanomedicine has emerged to improve drug delivery efficiency due to their superior targeting ability. By tailoring the properties of nanoparticle, including size, shape, surface chemistry, site‐specific drug delivery in organ, cellular, and subcellular level could be achieved. This minireview highlights recent advances in the development of targeted drug delivery system for disease therapy.