Open AccessSupramolecular design based activatable magnetic resonance imaging
Author(s) -
Geng WenChao,
Zheng Zhe,
Guo DongSheng
Publication year - 2021
Publication title -
view
Language(s) - English
Resource type - Journals
eISSN - 2688-268X
pISSN - 2688-3988
DOI - 10.1002/viw.20200059
Subject(s) - magnetic resonance imaging , supramolecular chemistry , nanotechnology , materials science , nuclear magnetic resonance , medicine , chemistry , radiology , physics , molecule , organic chemistry
Magnetic resonance imaging (MRI) has been widely used in clinical diagnosis. In recent years, activatable MRI probes responding to specific changes in their microenvironment have been developed. The signal of the MRI probe can be modulated based on supramolecular design, which can include properties such as self‐assembly and molecular recognition. In this review, we summarize the activatable MRI probes based on the design principles of supramolecular chemistry. We also discuss the current challenges and the future perspectives for how activatable MRI can achieve more extensive clinical applications for cancer therapy.