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Prenatal diagnosis of primary pulmonary hypoplasia in fraternal twins
Author(s) -
Chen S.,
Ursell P. C.,
Adatia I.,
Hislop A. A.,
Giannikopoulos P.,
Hornberger L. K.
Publication year - 2010
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.7520
Subject(s) - medicine , pulmonary hypoplasia , hypoplasia , autopsy , histopathology , fetus , prenatal diagnosis , pathology , pregnancy , surgery , genetics , biology
Primary pulmonary hypoplasia is a rare, usually lethal, condition presenting only after birth without other congenital abnormalities. We describe the first case of fraternal twins diagnosed prenatally with primary pulmonary hypoplasia. Both had diffuse hypoplasia of the pulmonary arteries initially identified by fetal echocardiography and confirmed at autopsy following termination. These cases permit examination of the histopathology of this disease in the fetal stage of development. Copyright © 2009 ISUOG. Published by John Wiley & Sons, Ltd.