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‘Big‐eyed frog’ sign on spatiotemporal image correlation (STIC) in the antenatal diagnosis of transposition of the great arteries
Author(s) -
Shih J. C.,
Shyu M. K.,
Su Y. N.,
Chiang Y. C.,
Lin C. H.,
Lee C. N.
Publication year - 2008
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.5369
Subject(s) - great arteries , medicine , atrioventricular valve , fetal echocardiography , fetus , great vessels , aorta , anatomy , transposition (logic) , aortic arch , prenatal diagnosis , pulmonary artery , cardiology , radiology , heart disease , pregnancy , artificial intelligence , ventricle , biology , computer science , genetics
Objective To determine the value of simultaneous visualization of the cross‐sectional view of both atrioventricular (AV) valves, the pulmonary artery and the aorta (en‐face view of the AV valves and great vessels) in the identification of fetuses with transposition of the great arteries (TGA). Methods This was a retrospective analysis of volume datasets obtained with the spatiotemporal image correlation (STIC) technique from 56 fetuses with and 30 fetuses without congenital heart defects. Volume datasets were reviewed offline to compare the en‐face view of the AV valves and great vessels between fetuses with normal echocardiography and those with TGA. Results The en‐face view of both AV valves and great vessels in fetuses with TGA displayed the main pulmonary artery situated side‐by‐side with the aorta (‘big‐eyed frog’ sign). In contrast, fetuses with normal hearts did not have this characteristic sonographic sign. This novel sonographic sign also helped to identify additional cases of TGA in 17 fetuses with complex heart defects. Conclusion The big‐eyed frog sign may prove helpful in the prenatal diagnosis of TGA. Copyright © 2008 ISUOG. Published by John Wiley & Sons, Ltd.