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EP16.09: Prenatal diagnosis of fetal heterotaxy syndrome by ultrasound: a case report
Author(s) -
Wang Y.,
Ge T.,
Chen W.
Publication year - 2019
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.21420
Subject(s) - medicine , fetus , inferior vena cava , ventricle , autopsy , dissection (medical) , aortic arch , anatomy , aorta , cardiology , radiology , pregnancy , genetics , biology
A 29-year-old pregnant woman was referred to our hospital for fetal ultrasonography at 24 weeks of gestation. Her personal and family history was unremarkable. Two-dimensional ultrasound and color Doppler were performed. The sonographic examination showed the fetus had a right-sided stomach, and the abdominal aorta and inferior vena cava were on the left side of the spine (Figure 1). Fetal left ventricle was significantly smaller than the right ventricle, and the atrioventricular septal was completely defected. The aortic arch was located on the right side of the trachea, and the pulmonary artery was narrow. The pulmonary veins flowed into the right atrium. The prenatal ultrasonographic diagnosis was fetal heterotaxy syndrome and complex cardiac malformations. The parents decided to terminate the pregnancy, and the consent for postmortem autopsy was obtained. At autopsy, Organ dissection revealed a midline liver, a right-sided stomach, asplenia, two lobar bronchi and four-lobed lungs with bilateral main bronchi. Cardiovascular dissection showed a stenotic left ventricle, complete atrioventricular septal defect with common atrioventricular valve, right aortic arch with left brachiocephalic trunk, right common carotid artery and right subclavian artery, pulmonary atresia, anomalous draining of the pulmonary veins to the right atrium. The thoracic part of the inferior vena cava was on the right side of the spine, and the abdominal part is turned to the left side of the spine. Figure 1. Prenatal ultrasonography at 24 weeks gestation: a right-sided stomach, abdominal aorta and inferior vena cava on the left side of the spine. AA:abdominal aorta; IVC: inferior vena cava; ST: stomach; GB:gallbladder.