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EP03.09: Placenta volume at 10–12 weeks of gestation is a predictor of preterm delivery
Author(s) -
Park I.,
Wie J.
Publication year - 2019
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.21155
Subject(s) - medicine , gestation , receiver operating characteristic , obstetrics , confidence interval , odds ratio , prospective cohort study , pregnancy , gestational age , preeclampsia , gynecology , surgery , genetics , biology
Methods A prospective cohort study including women with single pregnancies who underwent sonogram between 10-12 weeks of gestation. PV and 3D Doppler indices including vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were measured using 3D power Doppler imaging and the VOCAL technique. Preterm delivery is defined as a spontaneous delivery before 37 weeks of gestation with labor or premature rupture of membrane. Cases of preeclampsia was excluded. The predictive ability of each variable was evaluated using receiver-operating characteristic (ROC) curves. Conclusion The study suggests that low 3D PV between 10 -12 weeks of gestation is associated with subsequent spontaneous preterm delivery. Results Results: Of 342 women included, 300 women were followed until delivery and preterm delivery was occurred in 35 women. Low Zvalue of PV, VI, FI, and VFI were significantly associated with preterm delivery by MannWhitney U-test. (p= 0.002, 0.025, 0.029 and 0.013, respectively). Multivariate analysis showed that these factors were was significantly associated with preterm delivery. Factor Preterm delivery (n=33) Non-affected (n=243) P value