EP02.40: Amniotic fluid immune/inflammatory proteins in an asymptomatic short cervix (≤ 25mm) and cervical insufficiency and their association with length of latency | Zendy

Lee Y. | Zendy; Park K. | Zendy; Park Y. | Zendy; Hong S. | Zendy; Park J. | Zendy; Kim Y. | Zendy

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EP02.40: Amniotic fluid immune/inflammatory proteins in an asymptomatic short cervix (≤ 25mm) and cervical insufficiency and their association with length of latency

Author(s) -

Lee Y.,

Park K.,

Park Y.,

Hong S.,

Park J.,

Kim Y.

Publication year - 2019

Publication title -

ultrasound in obstetrics and gynecology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.202

H-Index - 141

eISSN - 1469-0705

pISSN - 0960-7692

DOI - 10.1002/uog.21141

Subject(s) - medicine , cervical insufficiency , cervix , chorioamnionitis , gastroenterology , pregnancy , gestational age , obstetrics , gynecology , cancer , biology , genetics

Study design • A retrospective study • 129 women with cervical insufficiency (cervical dilatation ≥ 10mm, n=80) or a short cervix (cervical length ≤ 25mm, n=49) • Inclusion criteria Singleton pregnancies (17 to 27 weeks) Absence of preterm labor and PPROM • AF obtained by transabdominal amniocentesis Measured LBP, IL-8, MMP-9, thrombospondin-2, APRIL, lipocalin-2, M-CSF, and S100 A8/A9 using ELISA kit • Primary outcome Comparison of AF levels of various proteins in cervical insufficiency vs. a short cervix. SPTD < 32 weeks

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