Premium
EP02.01: Gender‐specific effect of maternal HbA1c levels on placental volume
Author(s) -
Goletzke J.,
Pagenkemper M.,
Rüber F.,
Sirico A.,
Arck P.,
Hecher K.
Publication year - 2019
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.21102
Subject(s) - medicine , fetus , obstetrics , confounding , pregnancy , prospective cohort study , placenta , 3d ultrasound , gynecology , physiology , ultrasound , biology , genetics , radiology
Methods Analyses were based on prospective data in each trimester from 100 women of the low-risk pregnancy cohort study called PRINCE (50 male and female, respectively) Voluson E8 (3-5 MHz transducer) and placental volume calculated using 3D and VOCAL technique Multivariate linear regression models examined cross-sectional the association between metabolic parameters and placental volume Student’s t-test and Mann-WhitneyU test to test for gender differences Conclusion Despite normal HbA1c values, our results indicate a gender specific effect of HbA1c on placental volume and of placental volume on AAWT. This supports evidence of a fetal gender effect on the risk of metabolic perturbations. Figure 1: Univariate association between first trimester HbA1c and placental volume stratified by fetal gender.