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Fetal blood sampling in twin pregnancies
Author(s) -
Antsaklis A.,
Daskalakis G.,
Souka A. P.,
Kavalakis Y.,
Michalas S.
Publication year - 2003
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.211
Subject(s) - chorionic villus sampling , medicine , amniocentesis , obstetrics , fetus , miscarriage , pregnancy , blood sampling , twin pregnancy , prenatal diagnosis , sampling (signal processing) , gynecology , genetics , filter (signal processing) , computer science , computer vision , biology
Objective To evaluate the role of fetal blood sampling for prenatal diagnosis in twin pregnancies. Methods This was a retrospective study of 84 twin pregnancies that had undergone fetal blood sampling between the years 1977 and 2000. These results were compared with those from a similar study on amniocentesis and chorionic villus sampling. Results Miscarriage occurred in 3.6% of cases after fetal blood sampling. The total fetal loss rate was 13.6% and the fetal loss that could be attributed to the procedure was 8.2%. The procedure‐related fetal loss rate was dependent on the indication for fetal blood sampling. The rates of preterm delivery at ≤ 32 weeks, preterm delivery at ≤ 35 weeks, perinatal mortality at ≤ 28 weeks, perinatal mortality at > 28 weeks and neonatal mortality were 16.9%, 28.3%, 10.9%, 3.1% and 7.7%, respectively. Conclusion Fetal blood sampling in twin pregnancies carries higher risks for the fetus than do amniocentesis and chorionic villus sampling. However, it remains useful in evaluating the fetal condition in special circumstances such as hydrops and infection. Copyright © 2003 ISUOG. Published by John Wiley & Sons, Ltd.