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P06.12: Umbilical vein flow predicts adverse perinatal outcome in late fetal growth retardation at the time of the diagnosis
Author(s) -
Rizzo G.,
Mappa I.,
Mattioli C.,
Coccia L.,
Bitsadze V.,
Makatsarya A.,
D'Antonio F.
Publication year - 2019
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.20932
Subject(s) - medicine , umbilical artery , fetal distress , apgar score , obstetrics , uterine artery , middle cerebral artery , fetus , umbilical vein , caesarean section , pregnancy , cardiology , gestation , biochemistry , genetics , chemistry , ischemia , in vitro , biology
The primary outcome was SGA, defined as a baby with birth weight < 10th centile according with INTERGROWTH-21st standards. Sensitivity and specificity were calculated. Results: UtA Doppler assessment and birth weight were available in 864 women. Amongst those women, neonatal SGA occurred in 51 (5.90%), UtA was abnormal in 91% of all cases. The overall sensitivity, specificity, positive and negative predictive value were, 33, 88, 16, and 95%, respectively. In the low and intermediate-low risk group sensitivity and negative predictive value were similar to the all population (33, and 96%, respectively) (group A and B). SGA rate detection in the intermediate-low risk group doubled (from 8 to 16 cases). In the intermediate-high and high risk groups (C, D), sensitivity was higher (58%); with a lower negative predictive value (91%). Conclusions: UtA Doppler assessment in the second trimester, as a part of a multiparamenter test for screening for SGA, improves detection rate, especially in the subgroup of patients with risk factors for SGA. Negative predictive value in low-risk women can justify its use routinely.