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OP05.08: Role of chromosomal microarrays analysis in identifying pathogenetic variants in fetuses with single or multiple ultrasound abnormalities
Author(s) -
Azzaretto V.,
Vitucci A.,
Cavalli C.,
Izzi C.,
Signorelli M.,
Prefumo F.,
Fichera A.,
Dordoni C.,
Zanatta V.,
Grati F.,
Sartori E.
Publication year - 2019
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.20695
Subject(s) - karyotype , fetus , medicine , copy number variation , prenatal diagnosis , pathological , microarray , chromosome , obstetrics , pathology , genetics , pregnancy , biology , genome , gene , gene expression
Materials and Methods A retrospective study of pregnancies attending our centre from September 2017 to September 2018. All cases with CMA indicated by joint recommendations from the Italian Societies of Obstetric and Gynecological Ultrasound (SIEOG) and Human Genetics (SIGU) were included: single or multiple fetal structural anomalies detected by ultrasound; nuchal translucency ≥3.5 mm; early fetal growth restriction (eIUGR).