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EP08.17: Vanishing cerebellum as a complication of myelomeningocele
Author(s) -
Ochoa J.H.,
Mangupli P.,
Pautasso J.
Publication year - 2018
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.19902
Subject(s) - cerebellum , medicine , fourth ventricle , anatomy , echogenicity , foramen magnum , posterior inferior cerebellar artery , radiology , ultrasound , vertebral artery
We followed cysts in the majority (60%) of fetuses with normal anomaly scan. Results: The CVI cysts were more common in fetuses with brain anomaly compared to normal fetuses and fetuses with extra-CNS anomalies (23% versus 18.3% and 18% respectively; p value<0.01). The most common brain anomaly in fetuses with cyst was Dandy–Walker spectrum (47%) and in fetuses without cyst was ventriculomegaly (36%). The mean size of CVI cysts in normal fetuses was 4.6± 1.1mm (3-9.5mm). Also in fetuses with brain abnormality it was 9.2±3.7mm (3.3-16mm) compared to 5.8±1.9mm (3.9-9.7mm) in fetuses with extra-CNS anomalies. There was a significant difference between cysts size in normal fetuses and fetuses with brain anomalies (p value<0.01) and the cut-point was 7.1mm with a sensitivity of 70%, specificity of 98%. In normal group, only 3 cases had cyst size larger than 7.1mm and in these cases and all other followed cases the cysts resolved during pregnancy or after birth. Conclusions: The prevalence of CVI cysts is more common in fetuses with brain anomaly compared to normal fetuses and fetuses with extra-CNS anomalies. In fetuses with a CVI cyst size >7.1 mm in second trimester you need a more detailed brain examination. In normal fetuses with isolated CVI cysts, usually outcome is favourable.