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P11.05: Periconceptional maternal folate status and the impact on embryonic head and brain structures
Author(s) -
Husen S.,
Kemper N.,
Go A.,
Willemsen S.,
SteegersTheunissen R.P.
Publication year - 2018
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.19699
Subject(s) - medicine , population , quartile , pregnancy , offspring , gestation , andrology , obstetrics , physiology , nuclear medicine , biology , genetics , confidence interval , environmental health
Natural folate and synthetic folic acid provide one-carbon moieties for cell multiplication and epigenetic programming. We hypothesize that growth and development of embryonic head and brain structures are influenced by maternal folate status. Our aim is to investigate whether the periconceptional maternal folate status influences the sizes of embryonic head and brain structures using three-dimensional ultrasound (3D-US). Aim – To investigate the influence of maternal folate status on embryonic head and brain structures using three-dimensional ultrasound.