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P04.10: Correlation of changes in Doppler flow with pregnancy outcomes in early‐ and late‐fetal growth restriction
Author(s) -
Zhang L.,
Sun L.,
Wu Q.,
Han J.,
Zhang N.,
Li Z.
Publication year - 2018
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.19653
Subject(s) - medicine , ductus venosus , middle cerebral artery , fetus , youden's j statistic , pregnancy , cardiology , pulsatility index , umbilical artery , obstetrics , receiver operating characteristic , ischemia , genetics , biology
The incidence of FGR is rising due to a large number of the elderly pregnant women since Two Children Policy open in China. It has been reported that FGR was significant related to adverse pregnancy outcome with high prenatal mortality and morbidity including prematurity, respiratory distress syndrome and necrotizing enterocolitis and so on. The study is to insight into the changes in fetal Doppler flow of early-onset FGR and late-onset FGR respectively by ultrasound evaluation and to explore ultrasound predictors associated with pregnancy outcome. Methods A total of 77 early-onset FGR and 100 lateonset FGR were recruited in our study with the normal controls established respectively. Ultrasound evaluation indicators included fetal growth, UA, DV, MCA and MPI. The pregnancy outcomes of all cases were followed up. Results Early-onset FGR had increased UA-PI, DVPI and MPI, while decreased MCAPI and CPR. Moreover, only increased MPI and decreased and late fetal growth restriction. UA-PI and MPI should be monitored in order to improve pregnancy outcome, especially for early-onset FGR fetuses which tend to be with a higher perinatal morbidity and mortality rate than late-onset FGR fetuses. Figure 1. Ultrasound Doppler spectrum of MPI in normal fetus