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Placental histology findings in relation to pre‐eclampsia: implications for interpretation of retrospective studies
Author(s) -
Sebire N. J.
Publication year - 2017
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.17498
Subject(s) - medicine , blinding , interpretation (philosophy) , selection bias , hindsight bias , retrospective cohort study , recall bias , subconscious , eclampsia , relation (database) , clinical psychology , pathology , pregnancy , cognitive psychology , psychology , alternative medicine , randomized controlled trial , database , biology , computer science , programming language , genetics
In this issue Khalil et al. report the findings of a systematic review of studies reporting placental histological features in relation to pre-eclampsia (PET).(1) The main findings of this study were first, that whilst certain histological patterns were more common in PET than controls, similar features were also noted in unaffected cases, and secondly, that the results were related to whether the histological features in the studies were assessed blindly, with significantly greater apparent differences between groups reported in unblinded studies.