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Birth weight in live births and stillbirths
Author(s) -
Poon L. C. Y.,
Tan M. Y.,
Yerlikaya G.,
Syngelaki A.,
Nicolaides K. H.
Publication year - 2016
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.17287
Subject(s) - medicine , obstetrics , birth weight , live birth , gestational age , pregnancy , population , gestation , mcnemar's test , small for gestational age , biology , statistics , genetics , mathematics , environmental health
Objective To establish a normal range of birth weights for gestational age at delivery and to compare the proportion of live births and stillbirths that are classified as small‐for‐gestational age (SGA) according to our normal range vs that of the INTERGROWTH‐21 st standard. Methods The study population comprised 113 019 live births and 437 (0.4%) stillbirths. The inclusion criterion for establishing a normal range of birth weights for gestational age was the live birth of a phenotypically normal neonate ≥ 24 weeks' gestation and the exclusion criteria were smoking and prepregnancy hypertension, diabetes mellitus, systemic lupus erythematosus or antiphospholipid syndrome, pre‐eclampsia, gestational hypertension, gestational diabetes mellitus or iatrogenic preterm birth for fetal growth restriction in the current pregnancy. Inclusion criteria were met by 92 018 live births. The proportions of live births and stillbirths with birth weights < 5 th and < 10 th percentiles of our normal range and those according to the INTERGROWTH‐21 st standard were determined and compared by the chi‐square test and McNemar test. Results The proportions of live births and stillbirths with a birth weight < 5 th percentile according to our standard were significantly higher than and discordant with the proportion according to the INTERGROWTH‐21 st standard (live birth: 5.6% vs 3.4%; stillbirth: 37.2% vs 22.7%). Similarly, the proportion of live births and stillbirths with a birth weight < 10 th percentile according to our standard were significantly higher than and discordant with those according to the INTERGROWTH‐21 st standard (live birth: 11.2% vs 6.9%; stillbirth: 44.3% vs 32.6%). Conclusion The INTERGROWTH‐21 st standard underestimates the proportion of SGA live births and stillbirths in our population. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.