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EP17.03: First trimester serum markers to predict pregnancy complications: Tunisian prospective study
Author(s) -
Bouzid A.,
Ayachi A.,
Trabelsi H.,
Menjli S.,
Mkaouar l.,
Mourali M.
Publication year - 2016
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.17028
Subject(s) - medicine , pregnancy , obstetrics , logistic regression , prospective cohort study , population , preeclampsia , fetus , predictive value , genetics , biology , environmental health
Results The prevalence of various pregnancy complications was 8. 6% for birth prematurely, 9. 2% for hypertension or preeclampsia, IUGR 5. 8% and 7. 3% for loss pregnancy. PAPP A levels were lower in fetal loss group (P = 0. 005), vascular disease group(P = 0. 001) and preterm delivery group(P = 0. 001). In addition, a lower rate of bHCG was associated with the occurrence of placental pathologies such as growth retardation (P = 0. 037) and hypertension (P = 0. 034) and appears to have no predictive value in the occurrence of preterm birth (P = 0. 76) and fetal loss (P = 0. 189). Logistic regression analysis showed a significant predictive value of these markers.