Prospective evaluation of the fetal heart using Fetal Intelligent Navigation Echocardiography ( FINE )

Objective To evaluate prospectively the performance of Fetal Intelligent Navigation Echocardiography ( FINE ) applied to spatiotemporal image correlation ( STIC ) volume datasets of the normal fetal heart. Methods In all women between 19 and 30 weeks' gestation with a normal fetal heart, an attempt was made to acquire STIC volume datasets of the apical four‐chamber view if the following criteria were met: (1) fetal spine located between 5‐ and 7‐o'clock positions; (2) minimal or absent shadowing (including a clearly visible transverse aortic arch); (3) absence of fetal breathing, hiccups, or movement; and (4) adequate image quality. Each STIC volume successfully acquired was evaluated by STICLoop ™ to determine its appropriateness before applying the FINE method. Visualization rates of fetal echocardiography views using diagnostic planes and/or Virtual Intelligent Sonographer Assistance ( VIS ‐Assistance®) were calculated. Results One or more STIC volumes (365 in total) were obtained successfully in 72.5% (150/207) of women undergoing ultrasound examination. Of the 365 volumes evaluated by STICLoop , 351 (96.2%) were considered to be appropriate. From the 351 STIC volumes, only one STIC volume per patient ( n = 150) was analyzed using the FINE method, and consequently nine fetal echocardiography views were generated in 76–100% of cases using diagnostic planes only, in 98–100% of cases using VIS ‐Assistance only, and in 98–100% of cases when using a combination of diagnostic planes and/or VIS ‐Assistance. Conclusions In women between 19 and 30 weeks' gestation with a normal fetal heart undergoing prospective sonographic examination, STIC volumes can be obtained successfully in 72.5% of cases. The FINE method can be applied to generate nine standard fetal echocardiography views in 98–100% of these cases using a combination of diagnostic planes and/or VIS ‐Assistance. This suggests that FINE could be implemented in fetal cardiac screening programs. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.