OP 13.08: Impact of ultrasound screening in timing of detection and prevalence of anencephaly in the Netherlands | Zendy

FleurkeRozema H. | Zendy; Leijden L.V. | Zendy; van de Kamp K. | Zendy; Pajkrt E. | Zendy; Bilardo C.M. | Zendy; Snijders R. | Zendy

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OP 13.08: Impact of ultrasound screening in timing of detection and prevalence of anencephaly in the Netherlands

Author(s) -

FleurkeRozema H.,

Leijden L.V.,

van de Kamp K.,

Pajkrt E.,

Bilardo C.M.,

Snijders R.

Publication year - 2014

Publication title -

ultrasound in obstetrics and gynecology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.202

H-Index - 141

eISSN - 1469-0705

pISSN - 0960-7692

DOI - 10.1002/uog.13763

Subject(s) - anencephaly , medicine , obstetrics , pregnancy , retrospective cohort study , gestational age , third trimester , gestation , pediatrics , fetus , gynecology , surgery , genetics , biology

Results During the study period 110 cases of anencephaly were diagnosed. Overall prevalence of anencephaly was 5. 4 per 10. 000 pregnancies. The majority of the cases (60%) was detected before 14 weeks gestation. The detection rate before 14 weeks of pregnancy was significantly higher in the Northwest compared to the Northeast. (p=. 003). During the study period, gestational age at the time of detection did not change significantly (p=. 579). The percentage of cases with additional (chromosomal) anomalies was 24. 5%.

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