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OP 13.08: Impact of ultrasound screening in timing of detection and prevalence of anencephaly in the Netherlands
Author(s) -
FleurkeRozema H.,
Leijden L.V.,
van de Kamp K.,
Pajkrt E.,
Bilardo C.M.,
Snijders R.
Publication year - 2014
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.13763
Subject(s) - anencephaly , medicine , obstetrics , pregnancy , retrospective cohort study , gestational age , third trimester , gestation , pediatrics , fetus , gynecology , surgery , genetics , biology
Results During the study period 110 cases of anencephaly were diagnosed. Overall prevalence of anencephaly was 5. 4 per 10. 000 pregnancies. The majority of the cases (60%) was detected before 14 weeks gestation. The detection rate before 14 weeks of pregnancy was significantly higher in the Northwest compared to the Northeast. (p=. 003). During the study period, gestational age at the time of detection did not change significantly (p=. 579). The percentage of cases with additional (chromosomal) anomalies was 24. 5%.