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P11 .08: Comparison of transcerebellar diameter and cisterna magna depth measurements by manual 2D versus 3D automated TCD program
Author(s) -
Kwon J.,
Kim Y.,
Kwon H.,
Choi K.,
Cho H.,
Kim Y.,
Park Y.,
Kim S.,
Lee K.,
Yoo J.
Publication year - 2013
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.13057
Subject(s) - cisterna magna , medicine , nuclear medicine , biparietal diameter , cisterna , ultrasound , gestational age , radiology , pregnancy , pathology , head circumference , cerebrospinal fluid , biology , cell , genetics , golgi apparatus
Objectives: Ultrasound has the potential to describe tissue characteristics of the cervix in addition to length toassess of preterm birth. Reproducible approaches to the quantification of ultrasound derived tissue characteristics of the cervix in pregnancy remain under investigation. 1. To develop a reproducible method for describing gray scale tissue characteristics using ‘Image J’ software and compare with other methods. 2. To investigate effects of machine settings on gray-scale analysis techniques Methods: A standardised method was developed to define the region of interest of stromal tissue on the posterior aspect of the cervix. One dataset was obtained for 50 healthy nulliparous women at 20 weeks gestation. Pixels in 9 ROIs were analysed using Image J histogram analysis. Further studies were performed on a large dataset of women delivering term or preterm analysed using a number of statistical texture feature approaches including histogram analysis, a co-occurrence matrix method, and texture feature number Results: Little variation of mean gray value of the corresponding ROI in images of different depth, suggested little effect of machine settings on Image J gray scale analysis. Large coefficients of variation were found in each ROI, indicating a high gray scale width of each histogram Conclusions: Analysis of longitudinal data from the database showed changes over gestation but more studies are needed to refine methodology and to correlate with outcomes. Ultrasound tissue characterisation of the cervix based on pixel intensity analysis can be standardised but require validation prior to clinical application.