OP05 .02: Corroboration of normal and abnormal fetal cerebral lamination on postmortem sonography with neuropathological examination | Zendy

Pugash D. | Zendy; Dunham C. P. | Zendy; Mayer C. | Zendy; Hendson G. | Zendy; Gag A. | Zendy

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OP05 .02: Corroboration of normal and abnormal fetal cerebral lamination on postmortem sonography with neuropathological examination

Author(s) -

Pugash D.,

Dunham C. P.,

Mayer C.,

Hendson G.,

Gag A.

Publication year - 2013

Publication title -

ultrasound in obstetrics and gynecology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.202

H-Index - 141

eISSN - 1469-0705

pISSN - 0960-7692

DOI - 10.1002/uog.12754

Subject(s) - medicine , autopsy , fetus , lamination , pathology , subplate , anatomy , cerebral cortex , pregnancy , biology , chemistry , organic chemistry , layer (electronics) , genetics

Results Full ultrasound/autopsy correlation was available in 18 fetuses. In 8 fetuses with normal brains, cerebral lamination patterns were considered to be normal in all 7 cases in which full autopsy was performed. High frequency of ultrasound is correlated with 5 distinct sonographically identified histological layers on higher magnification views. Among 14 fetuses with abnormal prenatal intracranial findings, three patients declined autopsy; malformations were confirmed in all 3 on post-mortem sonography. In 2/11 fetuses undergoing full autopsy, findings were inconclusive due to autolysis. However, the antenatal findings were confirmed by postmortem ultrasound.

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