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Severe fetal cytomegalovirus infection associated with cerebellar hemorrhage
Author(s) -
Ortiz J. U.,
Ostermayer E.,
Fischer T.,
Kuschel B.,
Rudelius M.,
Schneider K. T. M.
Publication year - 2004
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.1021
Subject(s) - medicine , cytomegalovirus , serology , fetus , amniotic fluid , pregnancy , amniocentesis , prenatal diagnosis , cytomegalovirus infection , obstetrics , polymerase chain reaction , pathology , human cytomegalovirus , herpesviridae , immunology , antibody , viral disease , virus , biochemistry , chemistry , biology , gene , genetics
Cytomegalovirus (CMV) is the most common cause of congenital infection worldwide. We report on a fatal fetal manifestation of primary maternal CMV infection including cerebellar hemorrhage and hydrops. The diagnosis was established by maternal serological tests, culture and polymerase chain reaction testing of amniotic fluid and fetal blood. The pregnancy was terminated. Postmortem examination confirmed the diagnosis. Copyright © 2004 ISUOG. Published by John Wiley & Sons, Ltd.