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Angiogenic and antiangiogenic factors before and after resolution of maternal mirror syndrome
Author(s) -
Llurba E.,
Marsal G.,
Sanchez O.,
Dominguez C.,
AlijotasReig J.,
Carreras E.,
Cabero L.
Publication year - 2012
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.10136
Subject(s) - medicine , resolution (logic) , artificial intelligence , computer science
Mirror syndrome is a rare condition that involves fetal hydrops, placentomegaly and severe maternal edema. The pathogenesis of this syndrome mimics endothelial dysfunction observed in pre‐eclampsia. We report a case of maternal mirror syndrome caused by bilateral fetal hydrothorax that resolved after intrauterine pleuroamniotic shunt placement. At the time of the clinical manifestation there was an antiangiogenic state similar to that seen in pre‐eclampsia, which resolved after fetal treatment. Our findings suggest that mirror syndrome is a manifestation of a broad spectrum of pathological conditions that induces an antiangiogenic state. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.