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Co‐production of microcystins and aeruginopeptins by natural cyanobacterial bloom
Author(s) -
Harada Kenichi,
Mayumi Tsuyoshi,
Shimada Takayuki,
Fujii Kiyonaga,
Kondo Fumio,
Park Hodong,
Watanabe Mariyo F.
Publication year - 2001
Publication title -
environmental toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.813
H-Index - 77
eISSN - 1522-7278
pISSN - 1520-4081
DOI - 10.1002/tox.1036
Subject(s) - bloom , microcystis , microcystis aeruginosa , algal bloom , mass spectrometry , chemistry , microcystin , cyanobacteria , environmental chemistry , biology , chromatography , bacteria , ecology , organic chemistry , phytoplankton , nutrient , genetics
The relationship between Microcystis composition and the production of microcystins and nontoxic peptides in bloom cells, which was regularly collected in Lake Suwa, Japan, in the summer season from 1991 to 1994, was investigated. In order to determine the structures of the nontoxic peptides, we collected large amounts of bloom materials from the same lake on July 23, 1991, and isolated three nontoxic peptides. They were named as aeruginopeptins 917S‐A, ‐B, and ‐C, and their structures were mainly determined by a mass spectrometry/mass spectrometry (MS/MS) technique as 19‐membered cyclic depsipeptides possessing the Ahp (3‐amino‐6‐hydroxy‐2‐piperidone) moiety. An analysis of the microcystins and aeruginopeptins in the collected bloom cells and their Microcystis composition suggested that the M. aeruginosa large cell size produces both microcystins and aeruginopeptins, and the production of both compounds is genetically closely related. © 2001 John Wiley & Sons, Inc. Environ Toxicol 16: 298–305, 2001