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Severe adult atopic dermatitis successfully treated with concurrent Unseiin and standard treatment
Author(s) -
Nakai Noriaki,
Katoh Norito
Publication year - 2015
Publication title -
traditional and kampo medicine
Language(s) - English
Resource type - Journals
ISSN - 2053-4515
DOI - 10.1002/tkm2.1011
Subject(s) - medicine , atopic dermatitis , itching , lactate dehydrogenase , refractory (planetary science) , dermatology , atopy , white blood cell , fexofenadine , desquamation , gastroenterology , allergy , immunology , pharmacology , biochemistry , chemistry , physics , astrobiology , enzyme
Case A 64 year‐old woman suffering from atopic dermatitis refractory to standard treatment presented for treatment of severe skin eruptions on the whole body. Outcome On her first visit, white blood cell count including eosinophils (3310/μL), serum lactate dehydrogenase ( LDH ; 460 IU/L), serum immunoglobulin E (19 694 IU/mL), and thymus and activation‐regulated chemokine ( TARC ; 58 250 pg/mL) were elevated. Oral treatment with fexofenadine hydrochloride and topical steroids were started, but the eruptions and itching did not significantly improve. On day 18, concurrent treatment with U nseiin 7.5 g/day was started. On day 81, remission of skin eruption, and normal TARC (396 pg/mL), eosinophils (200/μL), and LDH (187 IU/L) were confirmed. Conclusion Concurrent treatment with U nseiin and standard treatment may provide an effective treatment option for patients with atopic dermatitis refractory to standard treatment.