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Critical analysis of the value of the rabbit median nerve model for biomedical research on peripheral nerve grafts
Author(s) -
Ronchi Giulia,
Gambarotta Giovanna,
Morano Michela,
Fregnan Federica,
Pugliese Pierfrancesco,
Tos Pierluigi,
Geuna Stefano,
HaastertTalini Kirsten
Publication year - 2020
Publication title -
journal of tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.835
H-Index - 72
eISSN - 1932-7005
pISSN - 1932-6254
DOI - 10.1002/term.3036
Subject(s) - peripheral nerve , rabbit (cipher) , animal model , peripheral , regeneration (biology) , medicine , computer science , biomedical engineering , anatomy , biology , microbiology and biotechnology , computer security
The rabbit has been proposed to represent an animal model that allows studying peripheral nerve regeneration across extended gap lengths. We describe here our experiences with the rabbit median nerve model and the obstacles it comes along with. This short communication is meant to inform the community and to prevent other researcher from investing time and animal lives in a model with low translational power.