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Coating bone‐like apatite onto organic substrates using solutions mimicking body fluid
Author(s) -
Ohtsuki Chikara,
Kamitakahara Masanobu,
Miyazaki Toshiki
Publication year - 2007
Publication title -
journal of tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.835
H-Index - 72
eISSN - 1932-7005
pISSN - 1932-6254
DOI - 10.1002/term.3
Subject(s) - apatite , simulated body fluid , coating , crystallinity , materials science , layer (electronics) , chemical engineering , crystallite , nanotechnology , chemistry , mineralogy , composite material , metallurgy , engineering
Bone‐like apatite is a carbonated hydroxyapatite with a small crystallite and low crystallinity. The formation of a layer consisting of bone‐like apatite is an essential condition for bioactive materials to achieve direct bonding with living bone. A bone‐like apatite layer can be formed on the surface of organic substrates in a solution mimicking a body fluid when some functional groups are introduced to organic substrates. This process is a biomimetic process because a simulated body fluid and related solutions are used to deposit bone‐like apatite crystals and promote crystal growth. Coating of bone‐like apatite layers through biomimetic processes has received much attention in the fabrication of novel composites with bone‐bonding properties, i.e. bioactivity, and mechanical properties analogous to those of living bone tissues. This paper reviews recent developments in coating with bone‐like apatite layers using biomimetic processes. Copyright © 2007 John Wiley & Sons, Ltd.