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Bio‐electrospraying whole human blood: analysing cellular viability at a molecular level
Author(s) -
Mongkoldhumrongkul Napachanok,
Best Steve,
Aarons Emma,
Jayasinghe Suwan N.
Publication year - 2009
Publication title -
journal of tissue engineering and regenerative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.835
H-Index - 72
eISSN - 1932-7005
pISSN - 1932-6254
DOI - 10.1002/term.185
Subject(s) - computational biology , human blood , biology , microbiology and biotechnology , nanotechnology , chemistry , materials science , physiology
Bio‐electrosprays, pioneered in 2005, have undergone several developmental studies which have seen this technique evolve as a novel direct in vivo tissue engineering and regenerative medicinal strategy. Those studies have been a hallmark for electrosprays; however, in this communication we report our on‐going developmental investigations for exploring bio‐electrosprays as a potential medical device and diagnostic protocol. The studies reported here demonstrate the ability to directly jet whole human blood without affecting the genetic make‐up, which has been interrogated by way of reverse transcription–polymerase chain reaction (RT–PCR) in comparison to controls ( p = 0.7337). These studies demonstrate bio‐electrosprays as a possible diagnostic protocol. Copyright © 2009 John Wiley & Sons, Ltd.