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Reaching the Full Potential of Electroorganic Synthesis by Paired Electrolysis
Author(s) -
Zhang Wenzhao,
Hong Nianmin,
Song Lu,
Fu Niankai
Publication year - 2021
Publication title -
the chemical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.61
H-Index - 78
eISSN - 1528-0691
pISSN - 1527-8999
DOI - 10.1002/tcr.202100025
Subject(s) - electrolysis , redox , electrochemistry , biochemical engineering , combinatorial chemistry , computer science , nanotechnology , process engineering , chemistry , electrode , materials science , inorganic chemistry , engineering , electrolyte
Electroorganic synthesis has recently become a rapidly blossoming research area within the organic synthesis community. It should be noted that electrochemical reaction is always a balanced reaction system with two half‐cell reactions‐oxidation and reduction. Most electrochemical strategies, however, typically focus on one of the two sides for the desired transformations. Paired electrolysis has two desirable half reactions running simultaneously, thus maximizing the overall margin of atom and energy economy. Meanwhile, the spatial separation between oxidation and reduction is the essential feature of electrochemistry, offering unique opportunities for the development of redox‐neutral reactions that would otherwise be challenging to accomplish in a conventional reaction flask setting. This review discusses the most recent illustrative examples of paired electrolysis with special emphasis on sequential and convergent processes.