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Forging C‐SeCF 3 Bonds with Trifluoromethyl Tolueneselenosulfonate under Visible‐Light
Author(s) -
Louvel Dan,
Ghiazza Clément,
Debrauwer Vincent,
Khrouz Lhoussain,
Monnereau Cyrille,
Tlili Anis
Publication year - 2021
Publication title -
the chemical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.61
H-Index - 78
eISSN - 1528-0691
pISSN - 1527-8999
DOI - 10.1002/tcr.202000184
Subject(s) - trifluoromethyl , reagent , electron paramagnetic resonance , cyclic voltammetry , chemistry , photochemistry , spectroscopy , combinatorial chemistry , visible spectrum , luminescence , materials science , organic chemistry , optoelectronics , electrochemistry , electrode , physics , nuclear magnetic resonance , alkyl , quantum mechanics
This account highlights some of our recent work on photoinduced trifluoromethylselenolation reactions. This research program relies primarily on the design of a new key shelf‐stable selenating reagent that can be involved in various radical processes In particular, we demonstrated that trifluoromethylselenolation of arenes, alkenes, alkynes as well as aliphatic organic building blocks can be readily achieved under visible‐light irradiation. Mechanistic investigations based on 19 F NMR studies, EPR spectroscopy, cyclic voltammetry and luminescence studies allowed us to shed the light on the different proposed mechanisms in the designed methodologies. The applicative potential of these strategies was further demonstrated through the synthesis of bioactive analogue containing SeCF 3 motif.