Cover Picture: Development of Chaetocin and  S ‐Adenosylmethionine Analogues as Tools for Studying Protein Methylation (Chem. Rec. 12/2018 | Zendy

Sohtome Yoshihiro | Zendy; Sodeoka Mikiko | Zendy

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Cover Picture: Development of Chaetocin and S ‐Adenosylmethionine Analogues as Tools for Studying Protein Methylation (Chem. Rec. 12/2018

Author(s) -

Sohtome Yoshihiro,

Sodeoka Mikiko

Publication year - 2018

Publication title -

the chemical record

Language(s) - English

Resource type - Reports

SCImago Journal Rank - 1.61

H-Index - 78

eISSN - 1528-0691

pISSN - 1527-8999

DOI - 10.1002/tcr.201881201

Subject(s) - methylation , cover (algebra) , methyltransferase , substrate (aquarium) , chemistry , computational biology , biology , biochemistry , engineering , dna , mechanical engineering , ecology

The Cover picture shows chaetocin and S ‐adenosylmethionine analogues as tools for studying protein methylation regulated by protein methyltransferases (PMTs). Structural development of these densely‐functionalized molecules, in combination with the myriad PMTs, accelerates PMT inhibitor/substrate discovery. See the Personal Account by Y. Sohtome and M. Sodeoka (DOI: 10.1002/tcr.201800118).

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