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Organocatalytic Desymmetrization Reactions for the Synthesis of Axially Chiral Compounds
Author(s) -
Di Iorio Nicola,
Crotti Simone,
Bencivenni Giorgio
Publication year - 2019
Publication title -
the chemical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.61
H-Index - 78
eISSN - 1528-0691
pISSN - 1527-8999
DOI - 10.1002/tcr.201800194
Subject(s) - desymmetrization , atropisomer , enantioselective synthesis , organocatalysis , chemistry , field (mathematics) , realization (probability) , combinatorial chemistry , catalysis , stereochemistry , organic chemistry , mathematics , pure mathematics , statistics
The enantioselective synthesis of atropisomers is an emerging field, that in recent years reached fundamental results and put the bases for innovative applications. Organocatalysis is playing a central role in the realization of original synthesis for novel atropisomeric scaffolds. [1] In this short review, we would like to highlight the results obtained by our group and others in the field of axially enantioselective desymmetrization reactions using organocatalysis as main strategy.