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β‐Cyclodextrin: A Green and Efficient Supramolecular Catalyst for Organic Transformations
Author(s) -
Dalal Dipak S.,
Patil Dipak R.,
Tayade Yogesh A.
Publication year - 2018
Publication title -
the chemical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.61
H-Index - 78
eISSN - 1528-0691
pISSN - 1527-8999
DOI - 10.1002/tcr.201800016
Subject(s) - cyclodextrin , chemistry , supramolecular chemistry , catalysis , organic reaction , supramolecular catalysis , organic chemistry , organic synthesis , combinatorial chemistry , oligosaccharide , aqueous solution , organic molecules , selectivity , molecule
Abstract β‐Cyclodextrin is cyclic oligosaccharide possessing hydrophobic cavity, which binds the substrates selectively and catalyze number of organic transformations with high selectivity. It catalyzes the reaction by non‐covalent supramolecular bonding with reversible formation of host‐guest complexes as seen in enzymes. This account summarizes our efforts in designing a good number of important organic transformations using β‐cyclodextrin and its derivatives. These reactions were performed in neat, aqueous as well as organic media. Greener synthetic routes to a variety of biologically relevant organic molecules has been developed. The temperature, solvent and catalyst amount plays in important role in these reactions. β‐Cyclodextrin activates variety of organic compounds like aldehydes, ketones, anhydride, oximes, amines, nitriles and increases the rate of reactions.