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Transition‐Metal‐Catalyzed Asymmetric Hydrogenation and Transfer Hydrogenation: Sustainable Chemistry to Access Bioactive Molecules
Author(s) -
Ayad Tahar,
Phansavath Phannarath,
RatovelomananaVidal Virginie
Publication year - 2016
Publication title -
the chemical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.61
H-Index - 78
eISSN - 1528-0691
pISSN - 1527-8999
DOI - 10.1002/tcr.201600100
Subject(s) - transfer hydrogenation , transition metal , catalysis , organic synthesis , chemistry , combinatorial chemistry , molecule , enantioselective synthesis , catalytic hydrogenation , nanotechnology , organic molecules , organic chemistry , materials science , ruthenium
Over the last few decades, the development of new and highly efficient synthetic methods to obtain chiral compounds has become an increasingly important and challenging research area in modern synthetic organic chemistry. In this account, we review recent work from our laboratory toward the synthesis of valuable chiral building blocks through transition‐metal‐catalyzed asymmetric hydrogenation and transfer hydrogenation of C=O, C=N and C=C bonds. Application to the synthesis of biologically relevant products is also described.