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Synthesis of Organofluoro Compounds Using Methyl Perfluoroalk‐2‐ynoates as Building Blocks
Author(s) -
Sun Xuechun,
Han Jing,
Chen Jie,
Zhang Hui,
Cao Weiguo
Publication year - 2016
Publication title -
the chemical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.61
H-Index - 78
eISSN - 1528-0691
pISSN - 1527-8999
DOI - 10.1002/tcr.201500258
Subject(s) - chemistry , combinatorial chemistry , organic chemistry
This review provides an overview of several synthetic applications of methyl perfluoroalk‐2‐ynoates, leading to convenient preparation of many perfluoroalkylated compounds. The use of these important substrates in the synthesis of various five‐, six‐, and seven‐membered heterocycles, cyclopentadienes, and biphenyls is described, alongside a discussion of the mechanistic aspects of these reactions.